New man-made African swine fever in Chinese pig farms, likely caused by illegal vaccines

nivek

As Above So Below
New man-made form of African swine fever in Chinese pig farms, likely caused by illegal vaccines

Do you think it’s possible that we’ll see similar fall out with the experimental coronavirus vaccines?

A new form of African swine fever has been identified in Chinese pig farms. According to Reuters, industry insiders say that the disease was most likely caused by illegal vaccines, and serves as a fresh blow to the nation where the COVID-19 coronavirus was first identified. China is the world’s largest producer of pork.

Reuters reports that two new strains of African swine fever have infected over 1,000 sows on several farms run by New Hope Liuhe, which is China’s fourth-largest pork producer. Yan Zhichun, the company’s chief science officer, said that pigs fed by the company by contract farmers have also been infected.

Unlike the previously discovered African swine fever virus, the new strains are missing one or two genes, and do not kill the pigs. Instead, the disease causes a chronic condition that reduces the number of healthy piglets born. The company has performed a culling to prevent the spread of the disease.

As noted by Reuters, known infections remain limited, but the disease could slash pork output in China if further outbreaks occur. In 2018, swine fever decimated half of China’s 400 million-head pig herd. The price of pork remains at a record high due to the previous outbreak, and China has been under international pressure to increase its food security.

I don’t know where they come from, but we find some mild field infections caused by some sort of gene-deleted viruses,” Yan said.



Reuters reports:

Wayne Johnson, a Beijing-based veterinarian, said he diagnosed a chronic, or less-lethal, form of the disease in pigs last year. The virus lacked certain genetic components, known as the MGF360 genes. New Hope has found strains of the virus missing both the MGF360 genes and the CD2v genes, Yan said.

Research has shown that deleting some MGF360 genes from African swine fever creates immunity. But the modified virus was not developed into a vaccine because it tended to later mutate back to a harmful state.

Much like other diseases harmful to pigs, the newly discovered strains of African swine fever have the potential to contaminate meat outside of their immediate vicinity. Farmers believe that illegal vaccines have created accidental infections. Reuters says that the disease infects pigs that are fed on kitchen waste and is known to survive for months in some pork products.

China’s Ministry of Agriculture and Rural Affairs has issued at least three warnings against the use of illicit vaccines, warning farmers that they have the potential to carry severe side effects. Producers who are caught using the illegal vaccines may be charged with a criminal offense.

Last August, the Chinese government said that it would test pigs for different strains of the virus, as part of a nationwide investigation into the use of illicit vaccines. Although no studies have been published so far, reporting of recent outbreaks has been extensively covered up, according to Reuters, which produced a special report on the matter.

Scientists say that illegal vaccines have a risk of carrying the virus because even after the virus is weakened for the vaccine form so it does not cause serious illness, the disease itself can recover its virulence and spread. Reuters reports that a similar vaccine used in Spain in the 1960s caused chronic disease that complicated efforts to eradicate African swine fever for three decades. Since the outbreak, no nation has approved a vaccine for the disease.

According to Yan Zhichun, the newly discovered strains are “definitely man-made; this is not a natural strain.”

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nivek

As Above So Below
ARS scientists make advancements against African swine fever virus

Agricultural Research Service scientists at the Plum Island Animal Disease Center in Orient Point, New York, have made two important advancements against African swine fever virus, which causes a lethal disease in pigs.

Last year, the research team developed several vaccine candidates by deleting genes to attenuate (weaken) the virus. They used a technique called “gene editing” in which DNA can be directly inserted, deleted, modified, or replaced in the genome of a living organism. As a result of this research, the team has currently licensed four different ASF vaccine candidates to commercial partners for further development.

A recent change in regulatory status may speed up commercial work on the candidate vaccines, said Douglas Gladue, an ARS microbiologist at PIADC. “Three of our vaccine candidates have been removed from the Federal Select Agent list,” which is a list of agents and toxins that must be worked on in facilities with the highest level of biosafety (BSL3), he said. PIADC is one of only two BSL3 facilities in the United State authorized to work with ASFV. “Removal from the Select Agent list could pave the way for our vaccine candidates to be worked on in other facilities in the United States and worldwide,” he said.

In a second major advancement, after an intensive screening process, the ARS team identified a commercially available stable cell line for diagnostic labs to use specifically in testing for infectious ASFV. Until now, fresh swine macrophages (large white blood cells) were the only cells that would work in the diagnostic testing process. This required labs to continuously culture fresh cells so they would be ready if and when a sample arrived for testing.

Now, however, the researchers say this other cell line, from an African green monkey, works as well as macrophages, and it can be frozen until needed, eliminating the need for continuous culturing.

“The advantage is enormous. You can keep the cell line in the freezer until you need it, and then you can have it in culture within 2 days,” said ARS microbiologist Manuel Borca. It also frees diagnostic labs from the need to obtain donor pig blood and process the macrophages, he says.

Using the commercially available primate cell line rather than fresh swine macrophages will save time, labor, equipment, and money. These cells are now available to diagnostic labs, including the Foreign Animal Disease Diagnostic Laboratory, part of USDA’s Animal and Plant Health Inspection Service.

Gaining control over ASFV is crucially important to swine producers worldwide. Although the virus has not reached the United States, it is present in parts of Europe, Asia, and Africa. The disease is almost always fatal in swine, and outbreaks result in trade restrictions and significant economic losses globally.

The research team is currently awaiting news on patenting a third important advancement in the fight against ASFV.

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Shadowprophet

Truthiness
ARS scientists make advancements against African swine fever virus

Agricultural Research Service scientists at the Plum Island Animal Disease Center in Orient Point, New York, have made two important advancements against African swine fever virus, which causes a lethal disease in pigs.

Last year, the research team developed several vaccine candidates by deleting genes to attenuate (weaken) the virus. They used a technique called “gene editing” in which DNA can be directly inserted, deleted, modified, or replaced in the genome of a living organism. As a result of this research, the team has currently licensed four different ASF vaccine candidates to commercial partners for further development.

A recent change in regulatory status may speed up commercial work on the candidate vaccines, said Douglas Gladue, an ARS microbiologist at PIADC. “Three of our vaccine candidates have been removed from the Federal Select Agent list,” which is a list of agents and toxins that must be worked on in facilities with the highest level of biosafety (BSL3), he said. PIADC is one of only two BSL3 facilities in the United State authorized to work with ASFV. “Removal from the Select Agent list could pave the way for our vaccine candidates to be worked on in other facilities in the United States and worldwide,” he said.

In a second major advancement, after an intensive screening process, the ARS team identified a commercially available stable cell line for diagnostic labs to use specifically in testing for infectious ASFV. Until now, fresh swine macrophages (large white blood cells) were the only cells that would work in the diagnostic testing process. This required labs to continuously culture fresh cells so they would be ready if and when a sample arrived for testing.

Now, however, the researchers say this other cell line, from an African green monkey, works as well as macrophages, and it can be frozen until needed, eliminating the need for continuous culturing.

“The advantage is enormous. You can keep the cell line in the freezer until you need it, and then you can have it in culture within 2 days,” said ARS microbiologist Manuel Borca. It also frees diagnostic labs from the need to obtain donor pig blood and process the macrophages, he says.

Using the commercially available primate cell line rather than fresh swine macrophages will save time, labor, equipment, and money. These cells are now available to diagnostic labs, including the Foreign Animal Disease Diagnostic Laboratory, part of USDA’s Animal and Plant Health Inspection Service.

Gaining control over ASFV is crucially important to swine producers worldwide. Although the virus has not reached the United States, it is present in parts of Europe, Asia, and Africa. The disease is almost always fatal in swine, and outbreaks result in trade restrictions and significant economic losses globally.

The research team is currently awaiting news on patenting a third important advancement in the fight against ASFV.

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In my mind, I keep thinking while reading this, About the Coronavirus, And what I learned about How Viruses pass from animals to humans, And the reasons some diseases have more issues transmitting to humans than others. These differences between animals and humans are vast, A great many people tend to reiterate the old philosophy that we humans are just some higher form of an animal. I think we humans are in many ways vastly different from Animals, plants, even diseases.

5KGCWNhRpVz23KbJuDbE8fMFHANOG4npfbpCIwVuHOCyqTbtUAdm2_QKa65f1aRLzlOu7YhpNYswz3lAs5F509Lki5fC7tc24qe8Ux5_UV32HZy40mzYUqMTtwRN3RdBiuIvXw


Even The closest animals on earth are Crude and lacking Evolution compared to humans.
I mean even an osteologist would agree, There is more difference between humans and apes than there would be between A house cat and a lion.
And I mean Consider how diseases even kill us. it's almost never the diseases directly killing the person like a poison would, It's the body trying to fight the foreign invader and the toll it takes on the body that usually does someone in.


I stand by my original assessment, I believe we humans were tampered with genetically, Or Maybe even created entirely. If Evolution takes millions of years Then why does Charles darwins flow chart predate human life by 5.8 million years? The fact is, It took six million years for human life to evolve and in literally 200 thousand years we have this gigantic evolutionary advantage over our closest cousins?

I don't know, Think about it. We, humans, have this amazing evolutionary Advantage that literally puts us millions of years of evolution ahead of every other life form we have ever encountered.


We were either created Or Engineered, Either way, I don't feel we achieved this on our own.
 

pepe

Celestial
In my mind, I keep thinking while reading this, About the Coronavirus, And what I learned about How Viruses pass from animals to humans, And the reasons some diseases have more issues transmitting to humans than others. These differences between animals and humans are vast, A great many people tend to reiterate the old philosophy that we humans are just some higher form of an animal. I think we humans are in many ways vastly different from Animals, plants, even diseases.

5KGCWNhRpVz23KbJuDbE8fMFHANOG4npfbpCIwVuHOCyqTbtUAdm2_QKa65f1aRLzlOu7YhpNYswz3lAs5F509Lki5fC7tc24qe8Ux5_UV32HZy40mzYUqMTtwRN3RdBiuIvXw


Even The closest animals on earth are Crude and lacking Evolution compared to humans.
I mean even an osteologist would agree, There is more difference between humans and apes than there would be between A house cat and a lion.
And I mean Consider how diseases even kill us. it's almost never the diseases directly killing the person like a poison would, It's the body trying to fight the foreign invader and the toll it takes on the body that usually does someone in.


I stand by my original assessment, I believe we humans were tampered with genetically, Or Maybe even created entirely. If Evolution takes millions of years Then why does Charles darwins flow chart predate human life by 5.8 million years? The fact is, It took six million years for human life to evolve and in literally 200 thousand years we have this gigantic evolutionary advantage over our closest cousins?

I don't know, Think about it. We, humans, have this amazing evolutionary Advantage that literally puts us millions of years of evolution ahead of every other life form we have ever encountered.


We were either created Or Engineered, Either way, I don't feel we achieved this on our own.

When a species is near extinction do you think that nature pulls out the stops for it or could there be a cut of point in concern. I'd like to think that nature is selective and chooses where to work. I believe in a creator and I also believe in Darwins theory as correct.

Are animals evolving ?

I don't know if they are at all, not like us, we are definitely becoming smarter, faster, taller and stronger. Why feed all the branches when there can only be one successor, a tree will let a branch die for the good of the better ones as it can also direct poison to one leaf and discard it.

It's time again, the slow progression and seemingly instant arrival like the irresistible force and the immovable object.

I happen to believe in it all, except time that is, that one is in our heads.

Glad to see you are doing ok Shadow.
 

pepe

Celestial
I hit latest post in this thread and now see that Shadow has taken the World Web speed record for derailing a thread.

One and done man...lol.

Nice spot to land in though.
 

Shadowprophet

Truthiness
When a species is near extinction do you think that nature pulls out the stops for it or could there be a cut of point in concern. I'd like to think that nature is selective and chooses where to work. I believe in a creator and I also believe in Darwins theory as correct.

Are animals evolving ?

I don't know if they are at all, not like us, we are definitely becoming smarter, faster, taller and stronger. Why feed all the branches when there can only be one successor, a tree will let a branch die for the good of the better ones as it can also direct poison to one leaf and discard it.

It's time again, the slow progression and seemingly instant arrival like the irresistible force and the immovable object.

I happen to believe in it all, except time that is, that one is in our heads.

Glad to see you are doing ok Shadow.
Well, consider for a moment, If there is anything to evolution at all in Darwin's theory all of life came from some singular source and we all originated from that. Animals would have to be evolving if we are, In Darwin's theory there are a lot of missing links sure, But If humans are the only forms of life that are actually evolving that would place us even farther from our animal friends and make us something else entirely. That's one of the issues I have with Darwin's evolution, It pretty much states we came from the same place in life's grand scheme that their platypus did, we just evolved differently, and save for an unknown number of missing links here we are. I'm not saying evolution in it's entirety isn't a thing, But Darwins Version of Evolution is missing the mark.


Consider who Darwin really was, Sure he was a product of his times, But none the less, Even though his time period was more accepting of his and his actions, He was still a heroin fiend that preached on an on about how incest was some sort of great thing.. The man had glaring mental issues that his time period simply could not afford to highlight.

As did Sigmund Freud, did you ever consider why or how old Siggy was considered some sort of pioneer in his field yet his main claim to fame was claiming that everyone secretly had the hots for their parents? There are far too many historical figures that are given far too much credit just for being So high that no one could manage to properly understand them to adequately debate them... in my opinion anyway...


As for Thread derailing, Oh yes I am known for that. It's nonintentional though I think my mind just changes channels far more often than it should lol :p
 
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pepe

Celestial
Well, consider for a moment, If there is anything to evolution at all in Darwin's theory all of life came from some singular source and we all originated from that. Animals would have to be evolving if we are, In Darwin's theory there are a lot of missing links sure, But If humans are the only forms of life that are actually evolving that would place us even farther from our animal friends and make us something else entirely. That's one of the issues I have with Darwin's evolution, It pretty much states we came from the same place in life's grand scheme that their platypus did, we just evolved differently, and save for an unknown number of missing links here we are. I'm not saying evolution in it's entirety isn't a thing, But Darwins Version of Evolution is missing the mark.


Consider who Darwin really was, Sure he was a product of his times, But none the less, Even though his time period was more accepting of his and his actions, He was still a heroin fiend that preached on an on about how incest was some sort of great thing.. The man had glaring mental issues that his time period simply could not afford to highlight.

As did Sigmund Freud, did you ever consider why or how old Siggy was considered some sort of pioneer in his field yet his main claim to fame was claiming that everyone secretly had the hots for their parents? There are far too many historical figures that are given far too much credit just for being So high that no one could manage to properly understand them to adequately debate them... in my opinion anyway...


As for Thread derailing, Oh yes I am known for that. It's nonintentional though I think my mind just changes channels far more often than it should lol :p

Life to me feels linear and connected and has one origin, I see animals around me as rungs to the ladder which gives me a natural sense of appreciating all of them as having a somewhat unsuccessful journey for the sake of our prevalence.

The tree to me is hugely significant, meaning that all comes from one seed with branches that flourish and others that die or become stunted as they become not fit for purpose. When is the last time we saw a new species that impacts on our world. There is lots of them and I don't expect the world to see anything new again as we have capped it off as fit for the bill and the spark created in us ignites the torch we must carry to safety.

It's quite a theme that many geniuses have an odd ball in the aching bag. Secretly meaning unconscious and ask yourself why is it we have the sense of repulsion when thinking of parental incest. Nature knows what comes of it and creates an emotional reaction, no matter how hot the feeling is constant. I'm sure that in times gone by that it went on more than you would like to think and was ironed out as a root to failure. Not such a crazy notion to me as he speaks from beyond our bindings.

The flat fish who's eyes migrate to one side and then hides in the sand to catch a meal has big meaning to me and brings on the thought of evolution pulling out the stops as there was a time where it was under threat as a species.

Out of the frying pan and into the flying saucer.
 

michael59

Celestial
You lost me again, Pepe. Stop that! lol

Why do you think China would take a risk like this now. Especially since they are soley being blamed for the pandemic in the first place?

China has some of the highest IQ ratings in the world. Why would they be so stupid and careless at a time like this?

Sounds contrived to me.
 

pepe

Celestial
You lost me again, Pepe. Stop that! lol

Why do you think China would take a risk like this now. Especially since they are soley being blamed for the pandemic in the first place?

China has some of the highest IQ ratings in the world. Why would they be so stupid and careless at a time like this?

Sounds contrived to me.

Everybody has a price with no exceptions. Black market vaccine I'm guessing is much cheaper. We are all up to stuff like this with corners being cut but the downfall is when a nation like China or Japan fall foul, they have a big issue with honour and this I believe is what happened last year. I will never forget Trump in an interview saying he had spoken to Xi and had been asked if there had been any problem with an outbreak in October 19 and then he shrugged his shoulders.

Defending their honour has cost many lives.

Back on track.
 
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