Deadly Wuhan Coronavirus

nivek

As Above So Below

nivek

As Above So Below
First coronavirus patient had NO connection to Wuhan seafood market - so did the disease start elsewhere?

The first patient diagnosed with the novel coronavirus has been reported to be a bed-bound pensioner who had no connection to a food market in Wuhan where Beijing's officials say the outbreak began. The revelation, made by BBC, echoed with the information disclosed in a previous medical research, which has prompted Chinese people to speculate about the possible alternative sources of the deadly disease.

Over the weekend, a mysterious virus lab became the centre point of Chinese social media after online accounts suggested that the lethal virus had come from there - allegations the state-run institute has denied and branded as rumours.

Beijing's experts claim that the deadly coronavirus outbreak began at Huanan Seafood Wholesales Market in Wuhan. They believe the virus was passed onto humans through wildlife sold as food.


The 'patient zero' fell ill on December 1 - a week earlier than the date the Chinese officials said the first case emerged - and had not been to the marketplace in question, a study also revealed.

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nivek

As Above So Below
U.S. Coronavirus Cases Nearly Double With No End in Sight

Confirmed cases of the new, deadly coronavirus in the United States almost doubled over the holiday weekend thanks to the messy evacuation of Americans from a cruise ship in Japan, while fresh numbers from China suggested the disease might be deadlier than first believed.

The U.S. government evacuated 328 American passengers from Tokyo early Monday on two chartered cargo jets, leaving dozens others behind who preferred to stay on the Diamond Princess cruise ship—despite a strong disembarkation recommendation from the federal government. The U.S. Centers for Disease Control and Prevention said over the weekend that it recommended repatriation so that it could take responsibility for care of the Americans and “to reduce the burden on the Japanese healthcare system.”

All travelers from Japan were screened before boarding the aircraft “to prevent symptomatic travelers from departing Japan,” according to the CDC. But 14 people who ultimately proved to be infected with the disease were included in the evacuation anyway, with officials later explaining that the positive results came back as passengers were already heading to the airport.

Dr. William Walters, managing director of operational medicine at the State Department, told reporters Monday that authorities evacuated passengers without knowing their test results because it was “unpredictable” when the results would come back. None of the diagnosed evacuees were showing symptoms, and they flew home in separate chambers—made of 10-feet-tall plastic sheets—from the other 314 passengers. The government planned to house all uninfected evacuees for 14 days at federal quarantine sites at Travis Air Force Base in California and Joint Base San Antonio-Lackland in Texas.


(more on the link)

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nivek

As Above So Below
Breakthrough in Coronavirus Research Results in New Map to Support Vaccine Design

Researchers from The University of Texas at Austin and the National Institutes of Health have made a critical breakthrough toward developing a vaccine for the 2019 novel coronavirus by creating the first 3D atomic scale map of the part of the virus that attaches to and infects human cells.

Mapping this part, called the spike protein, is an essential step so researchers around the world can develop vaccines and antiviral drugs to combat the virus. The paper was published Wednesday, Feb. 19 in the journal Science.

The scientific team is also working on a related viable vaccine candidate stemming from the research.

Jason McLellan, associate professor at UT Austin who led the research, and his colleagues have spent many years studying other coronaviruses, including SARS-CoV and MERS-CoV. They had already developed methods for locking coronavirus spike proteins into a shape that made them easier to analyze and could effectively turn them into candidates for vaccines. This experience gave them an advantage over other research teams studying the novel virus.

“As soon as we knew this was a coronavirus, we felt we had to jump at it,” McLellan said, “because we could be one of the first ones to get this structure. We knew exactly what mutations to put into this, because we’ve already shown these mutations work for a bunch of other coronaviruses.”


The bulk of the research was carried out by the study’s co-first authors, Ph.D. student Daniel Wrapp and research associate Nianshuang Wang, both at UT Austin.

Just two weeks after receiving the genome sequence of the virus from Chinese researchers, the team had designed and produced samples of their stabilized spike protein. It took about 12 more days to reconstruct the 3D atomic scale map, called a molecular structure, of the spike protein and submit a manuscript to Science, which expedited its peer review process. The many steps involved in this process would typically take months to accomplish.

Critical to the success was state-of-the-art technology known as cryogenic electron microscopy (cryo-EM) in UT Austin’s new Sauer Laboratory for Structural Biology. Cryo-EM allows researchers to make atomic-scale 3D models of cellular structures, molecules and viruses.

“We ended up being the first ones in part due to the infrastructure at the Sauer Lab,” McLellan said. “It highlights the importance of funding basic research facilities.”

The molecule the team produced, and for which they obtained a structure, represents only the extracellular portion of the spike protein, but it is enough to elicit an immune response in people, and thus serve as a vaccine.

Next, McLellan’s team plans to use their molecule to pursue another line of attack against the virus that causes COVID-19, using the molecule as a “probe” to isolate naturally produced antibodies from patients who have been infected with the novel coronavirus and successfully recovered. In large enough quantities, these antibodies could help treat a coronavirus infection soon after exposure. For example, the antibodies could protect soldiers or health care workers sent into an area with high infection rates on too short notice for the immunity from a vaccine to take effect.


(more on the link)

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nivek

As Above So Below
Surge in untraceable clusters of coronavirus around the world sparks dire warnings from disease experts

Coronavirus experts are more worried that they are unable to trace where clusters of the bug are breaking out than they are about the rising numbers of infections.

In South Korea, Singapore and Iran, clusters of infections are leading to a jump in cases of the new viral illness outside China.

But as hot spots emerge around the globe, trouble finding each source - the first patient who sparks every new cluster - might signal the disease has begun spreading too widely for tried-and-tested public health steps to stamp it out.


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Toroid

Founding Member
PANIC-BUYING OF FOOD CLEARS STORES IN ITALY - CORONAVIRUS
The Panic has begun. As reported on this web site on Saturday (HERE) the world is now suddenly realizing the scope and deadliness of Coronavirus, and they are PANICKING. Store shelves are literally being CLEARED of food, as people desperately try to prepare for the coming Quarantines.

Those who waited to prepare, are now panicking to do so now.
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Dejan Corovic

As above, so bellow
Folks, you've just fallen for pure corporate hype. Media is spinning coronavirus to make more money.

Lethalitty of coronavirus is 2% in comparison with flue which is 1%. But flue killed last year 65,000 people, much more than coronavirus.

Here is an article from a Croatian paper, where a Croatian scientist, who is member of US academy of science, tries to calm down the hype. You can translate article with Google Translator:

Article in Croatian:
Ivan Đikić smiruje paniku oko koronavirusa; SARS i MERS bili su opasniji, ljudi se moraju smiriti

Translated article:
Google Translate

Google Translate:
Google Translate Web - iTools
 

wwkirk

Divine
A science article.
Report: Contagion Up to 10 Times Worse Than China Admits

Abstract
This paper uses new credible non-official sources of data to evaluate the incidence and impact of the novel coronavirus (COVID-19) outbreak in China. Based on the number of reported cremations and on reports of possibly more accurate numbers on cases that appeared briefly on Tencent and were suppressed, we have conducted a modeling study to estimate the incidence and other parameters of the outbreak, including the potential starting time. The numbers for cumulative cases, new cases per day, and cumulative deaths coming from the non-official data are all substantially higher by a factor of 5 to 10 (depending on the date of the data) than would be implied by the official Chinese government data. All sets of non-official data used here imply that the coronavirus outbreak began in October or late September 2019.
 

Dejan Corovic

As above, so bellow
whole thing is over-hyped. Mortality rate from coronavirus is about 2%, while flue is 1%. Last year 64,000 people died from flue and coronavirus is not even close to that figure. The way media portray it is like there is an epidemics of cholera.

From 100 infected, 80 get cured naturally, 15 have health consequences that can be treated without being hospitalized, 5 have life threats, 3 of those 5 pass away. All people who passed away in Italy have had very poor health or were suffering from major illnesses before they got infected.

Here is what Italian papers say (please use Google Translate)
L’ex muratore , gli anziani ricoverati: chi sono le vittime
Coronavirus, 325 casi in Italia. Altri tre morti in Lombardia e uno in Veneto, le vittime diventano 11/
 
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nivek

As Above So Below
https://www.sacbee.com/news/california/article240674471.html
First U.S. coronavirus case of unknown origin confirmed in Northern California, CDC says

Officials with the U.S. Centers for Disease Control and Prevention confirmed the nation’s first coronavirus case of unknown origin Wednesday in Northern California in the latest sign of the virus’ rapid spread.

“It is a confirmed case. There is one in Northern California,” CDC spokesman Scott Pauley told The Sacramento Bee just before 4 p.m. Wednesday. Pauley declined to elaborate.

It was immediately unknown where in Northern California the case was discovered, but officials have begun to trace the person’s contacts as they sleuth out where and how the person may have become infected and whether others have been exposed, The Washington Post reports.

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nivek

As Above So Below
US coronavirus cases rise to 60: More Diamond Princess evacuees quarantined on US military bases test positive for the killer virus as CDC warns Americans to prepare for 'inevitable' spread across the country

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More Diamond Princess cruise ship evacuees - including two not previously reported by state officials - tested positive for coronavirus, the CDC confirmed Wednesday.

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Toroid

Founding Member
Strange similarities to the coronavirus in the 1981 book "The Eye's of Darkness" by Dean Koontz.
The Eyes of Darkness - Wikipedia
2019-2020 coronavirus speculation[edit]
It has been noted that the novel has several similarities with the 2019–20 coronavirus outbreak.[3][4][5][6] In the original 1981 publication, the name of the infectious agent was Gorki-400. Beginning with a 1989 reprint, the name was changed to Wuhan-400. The 2019 coronavirus was first identified in Wuhan, China.
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Dejan Corovic

As above, so bellow
You are panicking about nothing. Flu kills up to 61,000 people every year and nobody bats an eyelid. Coronavirus killed only about 3,000 people so far.

Here are what US Center for Disease Control and Prevention officially reports:

" CDC estimates that influenza has resulted in between 9 million – 45 million illnesses, between 140,000 – 810,000 hospitalizations and between 12,000 – 61,000 deaths annually since 2010."

In other words, one still stands higher chance of becoming infected and dying from influenza than from coronavirus.
Coronavirus is not terminal illness, 98% of infected people survive!
 

Standingstones

Celestial
I’m waiting for some athlete or an actor or celebrity to come down with the Corona virus. I’m sure most people think this will never happen to them. When they see someone with money or fame get sick then the panic will set in.
 

Shadowprophet

Truthiness
I'm trying to keep a level head about this Coronovirus stuff. It's not just me I'm worried about though, I mean, My father and mother are elderly, And My brother has lung cancer and I have grandkids.

There is so much that can go wrong here and so much to worry about, It's kind of panicking me.
 
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