Deadly Wuhan Coronavirus

August

Metanoia
So I got a question. When you are vaccinated with the Coronavirus vaccine ( 2 doses I believe ) , does that mean if you walked into a room filled with Covid 19 infected people you won't catch it ? The vaccine has just landed in Australia today and a lot of people are wondering about how effective it will be ?

Pfizer coronavirus vaccine doses arrives in Australia, ahead of first jabs next week - ABC News

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nivek

As Above So Below
So I got a question. When you are vaccinated with the Coronavirus vaccine ( 2 doses I believe ) , does that mean if you walked into a room filled with Covid 19 infected people you won't catch it ? The vaccine has just landed in Australia today and a lot of people are wondering about how effective it will be ?

Pfizer coronavirus vaccine doses arrives in Australia, ahead of first jabs next week - ABC News

5616.jpg

You can still get the infection however it would be mild symptoms, these vaccines cannot prevent getting ill, but they will keep you from going to the hospital...Still have to mask up and be sanitary in public, here's a recent report below of people getting sick after being fully vaccinated...

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'Breakthrough' COVID-19 reported in 4 fully vaccinated individuals

Health officials in Oregon said they are investigating four so-called "breakthrough" cases of coronavirus that were detected in individuals two weeks after they received their second dose of vaccine. The illnesses range from asymptomatic to mild, according to a news release posted Friday.

"Such cases are not unexpected," the news release said. "Clinical trials of both vaccines presently in use included breakthrough cases. In those cases, even though the participants got COVID-19, the vaccines reduced the severity of illness."

Genome sequencing is underway, and officials expect results next week. Two of the cases are located in Yamhill County, and two others are in Lane County. Local health officials are investigating the origins of the four cases.


Overall the state has delivered at least 677,000 first and second doses of the vaccine. On Monday, the state expanded vaccine eligibility to include residents ages 75-79 a week after those over 80 began receiving the vaccine.

Oregon has recorded at least 2,137 COVID-19 related deaths since the pandemic began, and over 150,280 cases.

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August

Metanoia
You can still get the infection however it would be mild symptoms, these vaccines cannot prevent getting ill, but they will keep you from going to the hospital...Still have to mask up and be sanitary in public, here's a recent report below of people getting sick after being fully vaccinated...

...

'Breakthrough' COVID-19 reported in 4 fully vaccinated individuals

Health officials in Oregon said they are investigating four so-called "breakthrough" cases of coronavirus that were detected in individuals two weeks after they received their second dose of vaccine. The illnesses range from asymptomatic to mild, according to a news release posted Friday.

"Such cases are not unexpected," the news release said. "Clinical trials of both vaccines presently in use included breakthrough cases. In those cases, even though the participants got COVID-19, the vaccines reduced the severity of illness."

Genome sequencing is underway, and officials expect results next week. Two of the cases are located in Yamhill County, and two others are in Lane County. Local health officials are investigating the origins of the four cases.


Overall the state has delivered at least 677,000 first and second doses of the vaccine. On Monday, the state expanded vaccine eligibility to include residents ages 75-79 a week after those over 80 began receiving the vaccine.

Oregon has recorded at least 2,137 COVID-19 related deaths since the pandemic began, and over 150,280 cases.

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They start injecting people here on Monday. It will take 12 months to do everyone.
 

AD1184

Celestial
So I got a question. When you are vaccinated with the Coronavirus vaccine ( 2 doses I believe ) , does that mean if you walked into a room filled with Covid 19 infected people you won't catch it ? The vaccine has just landed in Australia today and a lot of people are wondering about how effective it will be ?

Pfizer coronavirus vaccine doses arrives in Australia, ahead of first jabs next week - ABC News

5616.jpg
There's this paper published in March, 2020 (so covers research conducted pre-Covid)

Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence

about vaccines in general, and what they do in terms of the pathogen's effects on the vaccinated individual, and on those individuals the vaccinated may pass the pathogen onto. The researchers used a chicken virus, and its vaccine, to study disease transmission in chickens in the presence of a partially-vaccinated population. Here is the abstract
Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This leakiness is concerning because it increases vaccination coverage required to prevent disease spread and can promote evolution of increased pathogen virulence. Despite leakiness, vaccination may reduce pathogen load, affecting disease transmission dynamics. However, the impacts on post-transmission disease development and infectiousness in contact individuals are unknown. Here, we use transmission experiments involving Marek disease virus (MDV) in chickens to show that vaccination with a leaky vaccine substantially reduces viral load in both vaccinated individuals and unvaccinated contact individuals they infect. Consequently, contact birds are less likely to develop disease symptoms or die, show less severe symptoms, and shed less infectious virus themselves, when infected by vaccinated birds. These results highlight that even partial vaccination with a leaky vaccine can have unforeseen positive consequences in controlling the spread and symptoms of disease.

Therefore
  • It is typical that vaccines do not completely prevent infection.
  • The viral load, symptom severity, and infective dose passed onto close contacts, is typically much lower in vaccinated individuals.
  • The viral load, symptom severity, and infective dose passed onto close contacts, is typically much lower in unvaccinated individuals who acquired their infection from a vaccinated individual, compared to those who acquired it from an unvaccinated individual.
  • Even imperfect vaccines can have an important disease-controlling effect.
 
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nivek

As Above So Below

Seven new highly contagious COVID-19 variants found across US

Seven new coronavirus variants have popped up in the US since last summer, according to a new study — and scientists worry they may be more contagious.

The new variants — each named after a bird —were detailed in a 25-page medical study published online Sunday, which has yet to be peer-reviewed.

The variants are alike in that each mutates the coronavirus’ 677th amino acid, found on the "spike" that the virus uses to attach itself to healthy cells — raising fears that the changes could make them more infectious.

"This stretch of Spike is important because of its proximity to a region key for virulence," Vaughn Cooper, one of the study’s senior authors and director of the University of Pittsburgh’s Center for Evolutionary Biology and Medicine, told CNN.

The mutations have been found by scientists across the country conducting genetic sequencing on positive COVID-19 tests.

They are:

  • "Robin 1," which "is found in over 30 US states, but predominates in the Midwest," according to the study. It was first detected in August.
  • "Robin 2," which was first found in a sample collected in early October in Alabama. Accordingly, it is most common in the Southeast.
  • "Pelican," which was first detected in Oregon in late October. However, it has been found in 12 other states, and is the only variant of the seven thus far detected abroad, popping up on tests in Australia, Denmark, India and Switzerland.
  • "Yellowhammer," which, like "Robin 2," is most common in the southeastern US. It first appeared in a sample from late November.
  • "Bluebird," which first appeared in August and is most common in the Northeast.
  • "Quail," which most commonly appears in opposing corners of the US, the Northeast and the Southwest. It was first detected in early October.
  • "Mockingbird," first found in late November and prevalent in the south-central US, as well as along the East Coast.
However, an overwhelming majority of positive coronavirus samples are never genetically sequenced, so it’s unclear just how widespread the variants may actually be and where they originated.

"I’d be quite hesitant to give an origin location for any of these lineages at the moment," Emma Hodcroft, another co-author of the study and an epidemiologist at the University of Bern, told the New York Times.

Also impossible to say at the moment is whether the mutations are, in fact, more virulent — as the available data is insufficient to determine whether they’ve truly spread at accelerated rates, or just benefited from conditions that are conducive to infection, such as a carrier attending a superspreader event.

However, other international variants — most notably the UK strain, which has been detected stateside, including in New York — have been found to be significantly more infectious than the garden-variety coronavirus, complicating efforts to quash the deadly bug for good.

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pepe

Celestial
One of my oldest and dearest friends is gravely ill and in the hospital. He's COVID positive but completely asymptomatic.
If he had passed in the hospital due to any of the immediately life threatening problems he would most likely be coded as another virus death.

They were about to ship him to a goddamned nursing home. Social services - they were going to warehouse him in a nursing home while he undergoes chemo and radiation. Of the two places in question you wouldn't board your dog there. We didn't let that happen.

But even after maybe 15000 people have died because of this exact stupidity nothing has changed except the governor got an Emmy.

Well done for keeping him out and I hope both you and your wife are well enough pigfarmer. It's numbers that help us and hinder us, things go out of the window when the numbers are up and well done. When my dad was taken into a home I wanted to be there everyday, I did three a week until he passed away and so glad I did. One of my bros did very little and has suffered the consequences internally.

Good luck to you PF.
 

pigfarmer

tall, thin, irritable
Woke up feeling about normal today. Nine days of this crap. Chest is still congested but is breaking up. I think some of the things coming out of me could possibly fly across the room and stick to my Science officer's Back. Eeeeew. In that case, six
feet ain't enough.

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My wife is a day or two behind me and is OK - except for one bad night it didn't seem to hit her as hard.

Now we can join the ranks of those who might or might not have some immunity that might or might not last some period of time while waiting for the vaccine that might or might not be completely effective that we definitely can't get.

Yeah, that's about it.
 

AD1184

Celestial
Covid-19: World's first human trials given green light in UK

Covid-19: World's first human trials given green light in UK

Healthy, young volunteers will be infected with coronavirus to test vaccines and treatments in the world's first Covid-19 "human challenge" study, which will take place in the UK.

The study, which has received ethics approval, will start in the next few weeks and recruit 90 people aged 18-30.

They will be exposed to the virus in a safe and controlled environment while medics monitor their health.
 

nivek

As Above So Below
Super Covid?...

UK and Californian coronavirus variants have MERGED into one: Rare combination event spotted in American patient could create strain that spreads rapidly and dodges immunity, scientists warn

A hybrid version of the coronavirus has surfaced in California after the British Kent variant and a strain found in the US merged together inside an infected person. The variant, not yet named, has only been spotted once but scientists fear there are likely to be more cases. Experts are worried because it carries mutations which appear to make it able to spread faster and also to slip past some of the immunity made from past infections or vaccines.

It was formed from the Kent Covid variant – known scientifically as B.1.1.7 – and a Californian variant called B.1.429. Scientists in the US claim they merged in a 'recombination event', the New Scientist reports. This happens when two different versions of the virus infect the same cell and then swap genes while they are reproducing, giving rise to a new variant.

Researchers have warned in the past that these events are possible but said they are 'unlikely' because they require very specific conditions and the coincidence of mostly uncontrollable events. They are more likely to happen during huge outbreaks.

It is believed to have happened in this instance because a number of mutations matching those on the Kent and California variants all appeared in the same place at once. There are no details of the patient and it is unclear whether the combination happened in them, or whether they caught the variant from someone else.

While experts have said there is no need to panic about new variants, one admitted recombination was 'dangerous' because it could change the virus so suddenly.

Britain's Government is clearly worried about the spread of variants that could escape immunity from the current vaccines and is likely to stretch out the lifting of lockdown rules into the summer in a bid to prevent an uncontrolled outbreak.


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(More on the link)

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nivek

As Above So Below
Japan finds new Covid-19 strain

Japan confirmed a new variant of Covid-19, and an infection cluster emerged at a Tokyo immigration facility, presenting new challenges as the country tries to overcome a third wave of the pandemic.

The new variant has been found in 91 cases in the Kanto area of eastern Japan and in 2 cases at airports, Chief Cabinet Secretary Katsunobu Kato told reporters on Friday.

The government is raising surveillance against mutant varieties as they may be more resistant to vaccines, which Japan started to distribute this week. "It may be more contagious than conventional strains, and if it continues to spread domestically, it could lead to a rapid rise in cases," Kato said.


The new strain appears to have originated overseas but is different from other types that have been found sporadically in Japan, according to the National Institute of Infectious Diseases.

It has the E484K mutation on the spike protein of the virus that has been found in other variants, which may undermine the effectiveness of vaccines.

Japan has reported 151 cases of variants from Britain, South Africa and Brazil, according to the health ministry. The nation has had more than 400,000 cases of Covid-19 with 7,194 fatalities. Meanwhile, 5 staff and 39 foreign detainees at a Tokyo immigration facility have tested positive for Covid-19.

All 130 detainees at the facility have been tested for the virus, according to a spokesperson for the Tokyo Regional Immigration Bureau. None of the cases is serious, and all infected detainees remain quarantined from others. The representative declined to comment on the nationality of the infected detainees, citing privacy concerns.

Japan's detention system for immigration law violators and asylum seekers has been widely criticized for its medical standards, monitoring of detainees and response to emergencies. "Many detainees are locked in a small, closed spaces," said Motoko Yamagishi, the head of a migrants-rights group. "It is regrettable that such a outbreak happened in the centre."

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August

Metanoia
Japan finds new Covid-19 strain

Japan confirmed a new variant of Covid-19, and an infection cluster emerged at a Tokyo immigration facility, presenting new challenges as the country tries to overcome a third wave of the pandemic.

The new variant has been found in 91 cases in the Kanto area of eastern Japan and in 2 cases at airports, Chief Cabinet Secretary Katsunobu Kato told reporters on Friday.

The government is raising surveillance against mutant varieties as they may be more resistant to vaccines, which Japan started to distribute this week. "It may be more contagious than conventional strains, and if it continues to spread domestically, it could lead to a rapid rise in cases," Kato said.


The new strain appears to have originated overseas but is different from other types that have been found sporadically in Japan, according to the National Institute of Infectious Diseases.

It has the E484K mutation on the spike protein of the virus that has been found in other variants, which may undermine the effectiveness of vaccines.

Japan has reported 151 cases of variants from Britain, South Africa and Brazil, according to the health ministry. The nation has had more than 400,000 cases of Covid-19 with 7,194 fatalities. Meanwhile, 5 staff and 39 foreign detainees at a Tokyo immigration facility have tested positive for Covid-19.

All 130 detainees at the facility have been tested for the virus, according to a spokesperson for the Tokyo Regional Immigration Bureau. None of the cases is serious, and all infected detainees remain quarantined from others. The representative declined to comment on the nationality of the infected detainees, citing privacy concerns.

Japan's detention system for immigration law violators and asylum seekers has been widely criticized for its medical standards, monitoring of detainees and response to emergencies. "Many detainees are locked in a small, closed spaces," said Motoko Yamagishi, the head of a migrants-rights group. "It is regrettable that such a outbreak happened in the centre."

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Just in time for the Olympics.
 

pigfarmer

tall, thin, irritable
Since we're all scientists as of late, isn't this what the plain old flu has been doing in terms of mutation ?
I am well aware of how many people have died. My wife and I are recovering from it right now. Also well aware that other people in other countries went through something different, I can only speak about what I see around me.

A virus that didn't mutate would be no fun - hope you kept the receipt.

We were all justifiably scared last year when we first heard about this, then it turned into the sort of pregnant anticipation that comes ahead of a big storm, then it got politicized and keeping people scared shitless was what the news cycle devoted itself to. Recently there have been news articles circulating about 'herd immunity by April' which sounds like a stretch to me but I suspect - and hope - that we'll be hearing more about that later in the year.

Locally the cases and hospitalizations are falling rapidly after the holiday shopping season.
 

August

Metanoia
So do you have have to have the Covid 19 vaccine and booster every year from now on just like the flu shot ? Or is it a one off jab ?
 

pigfarmer

tall, thin, irritable
So do you have have to have the Covid 19 vaccine and booster every year from now on just like the flu shot ? Or is it a one off jab ?

Been wondering myself. I didn't realize that the first vaccine injection provides something like 92% protection and the second shot brings it up to 94% - by whatever method they use to determine that. I'll get one when generally available but figure there are many others who need it more than I do. Have at it.
 
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